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Month: July 2020

Mechanism of action of Fluconazole

Fluconazole: mechanism, spectrum, resistance, pharmacokinetics, uses and side effects

July 14, 2020 Gaurab Karki 0

Fluconazole is a synthetic bis-triazole compound, where triazole is one of the classes of antifungal. It is basically used for the treatment of fungal infections, […]

Amphotericin B: mechanism, spectrum, pharmacokinetics, uses and side effects

July 13, 2020 Gaurab Karki 0

Amphotericin B is a macrocyclic polyene antibiotic derived from Streptomyces nodosus. It remains the drug of choice for many forms of deep fungal infection. Mechanism […]

Dynamics of disease transmission: Reservoir, Mode of transmission and Susceptible host

Dynamics of disease transmission: Reservoir, Mode of transmission and Susceptible host

July 9, 2020 Gaurab Karki 0

Diseases are transmitted from the source of infection to susceptible host. The medical model of infectious disease transmission consists of three interlinked chains. They are: […]

Hematopoiesis: Types of Haematopoietic stem cells, Process and Regulation

Hematopoiesis: Types of Haematopoietic stem cells, Process and Regulation

July 7, 2020 Gaurab Karki 0

Haematopoiesis Haematopoiesis is defined as the process of formation, development and differentiation of blood cells. The blood cells are formed from haematopoietic stem cells (HSCs) […]

G-protein coupled receptor (GPCR): β -adrenergic signalling pathway

G-protein coupled receptor (GPCR): β -adrenergic signalling pathway

July 7, 2020 Gaurab Karki 0

G-protein coupled receptors (GPCRs) G protein–coupled receptors (GPCRs) are receptors that are closely related with a member of the guanosine nucleotide–binding protein (G protein) family. […]

L-Pyrrolidonyl Arylamidase (PYR) test: Principle, Requirements, Procedure and Results

L-Pyrrolidonyl Arylamidase (PYR) test: Principle, Requirements, Procedure and Results

July 6, 2020 Gaurab Karki 0

Principle of PYR test: L-Pyrrolidonyl Arylamidase (PYR) test is one of the rapid tests employed for the identification of group a beta-hemolytic Streptococci and Enterococci […]

Decarboxylase test-Principle, Procedure and Results

July 6, 2020 Gaurab Karki 0

Principle of Decarboxylase test: Decarboxylases are a group of enzymes which acts by hydrolyzing an amino acid to form an amine. Decarboxylase test is mainly […]

Leucine Amino Peptidase (LAP) test: Principle, Procedure and Results interpretations

Leucine Amino Peptidase (LAP) test

July 6, 2020 Gaurab Karki 0

Principle: Leucine Amino Peptidase (LAP) test is one of the rapid tests which is employed for the detection of the enzyme leucine amino peptidase. The […]

Microdase (Modified Oxidase) test: Principle, Procedure and Results interpretation

Microdase (Modified Oxidase) test: Principle, Procedure and Results interpretation

July 6, 2020 Gaurab Karki 0

Principle: Microdase test is also termed as modified oxidase test. It is one of the rapid tests employed for the differentiation between Staphylococcus and Micrococcus […]

Somaclonal variation: Basis, Applications and limitations

Somaclonal variation: Basis, Applications and limitations

July 6, 2020 Gaurab Karki 0

Somaclonal variation The term somaclonal variation by Larkin and Scowcroft (1981) was given for the variability generated by the use of a tissue culture cycle. […]

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