Difference between Prokaryotic and Eukaryotic translation




Difference between Prokaryotic and Eukaryotic translation

Translation Prokaryotes Eukaryotes
Initiation factor Three (IF3, IF2, IF1) Nine  (eIF4F complex; eIF4E, eIF4G,eIF4A)
Ribosome 30S and 50S 40S and 60s
Shinedalgarno sequence at 5’ end Present (5’ UAAGGAGG3’). absent
Poly A tail at 3’end absent present
Elongation factor EF-TU, EF-TS, EF-G-GTP eEF1α, eEF1βϒ,eEF2
Release factors Three (RF1, RF2 and RF3) One (eRF)
Chain initiating aminoacid N-formyl methionine methionine
mRNA Polycistonic Monocistonic
Stability of mRNA unstable Quite stable
Rate of translation Faster process; adds 20 aminoacids per second Slower process; adds one aminoacid per cecond
Placement of AUG codon P-site By shinedalgarno sequence Scanning of mRNA

 

Difference between Prokaryotic and Eukaryotic translation