Difference between batch, fed-batch and continuous culture technique




Difference between batch, fed- batch and continuous culture technique

Difference between batch, fed-batch and continuous culture technique

Characteristics Batch culture Fed-batch culture Continuous culture
Cultivation system Closed type Semi-closed type Open type
Addition of fresh nutrition No Yes Yes
Volume of culture Constant Increases Constant
Removal of wastes No No Yes
Chance of contamination minimum Intermediate Maximum
Growth phase Lag, log, stationary and decline phase Lag, log , stationary and decline phase Lag and log phase
Log phase Shorter longer Longest and Continuous
Density of bacteria Change with time Change with time Remain same
Product yield Low Medium High

Difference between batch, fed-batch and continuous culture technique